How to establish the following identities without the help of calculus:
For positive integer $n, $ $$\sum_{1\le r\le n}\frac{(-1)^{r-1}\binom nr}r=\sum_{1\le r\le n}\frac1r $$
and $$\sum_{0\le r\le n}\frac{(-1)^r\binom nr}{4r+1}=\frac{4^n\cdot n!}{1\cdot5\cdot9\cdots(4n+1)}$$
You can always use Petkovsek's algorithm. It only requires some algebra to prove this and other problems alike.
You can read about it in the book $A=B$ (available free online).
Another thing is that derivation of polynomials is a completely algebraic operation.
You can always write instead of $(P(x))'|_{x=1}$ write $[P(x+1)-P(1)]/x|_{x=0}$, perhaps what is equivalent, rewrite in powers of $(x-1)$, which involves iterated division by $(x-1)$. [I just pressed Alt+F7 to try to compile the LaTeX] And little by little hide the calculus from the proof that you have.