I have happened to have proved this sum while attempting to prove another summation. Let $$S_n=\sum_{k=0}^{2n} {2k \choose k } {2n \choose k}\left( \frac{-1}{2} \right)^k$$ ${2k \choose k} $ is the coefficient of $x^0$ in $(x+1/x)^{2k}$. Consequently, $S_n$ is the coefficient of $x^0$ in $$f(x)= \sum_{k=0}^{2n} {2n \choose k}~\left (x+\frac{1}{x}\right)^{2k}~\left ( \frac{-1}{2}\right)^{k}=\left(1-\left(\frac{x+1/x}{\sqrt{2}}\right)^2 \right)^{2n} = 4^{-n} ~ \left(x^2+\frac{1}{x^2}\right)^{2n}.$$ Finally, the coefficient of $x^0$ in $f(x)$ is $$4^{-n}~{2n \choose n}=S_n.$$ I hope that you will find it interesting and prove it in some other way. Do try!
Proving that $\sum_{k=0}^{2n} {2k \choose k } {2n \choose k}\left( \frac{-1}{2} \right)^k=4^{-n}~{2n \choose n}.$
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On
We will use
$$
\frac1{1-x}\left(\frac{x}{1-x}\right)^k=\sum_{n=0}^\infty\binom{n}{k}x^n\tag1
$$
and
$$
(1-4x)^{-1/2}=\sum_{k=0}^\infty\binom{2k}{k}x^k\tag2
$$
Extracting the even part of $(1)$
$$
\begin{align}
\sum_{n=0}^\infty\binom{2n}{k}x^{2n}
=\frac12\left[\frac1{1-x}\left(\frac{x}{1-x}\right)^k+\frac1{1+x}\left(-\frac{x}{1+x}\right)^k\right]\tag3
\end{align}
$$
Compute the generating function of the sum we want
$$
\begin{align}
&\sum_{n=0}^\infty\sum_{k=0}^\infty\binom{2k}{k}\binom{2n}{k}\left(-\frac12\right)^kx^{2n}\tag4\\
&=\frac1{2-2x}\sum_{k=0}^\infty\binom{2k}{k}\left(-\frac{x}{2-2x}\right)^k
+\frac1{2+2x}\sum_{k=0}^\infty\binom{2k}{k}\left(\frac{x}{2+2x}\right)^k\tag5\\
&=\frac1{2-2x}\left(1+\frac{4x}{2-2x}\right)^{-1/2}
+\frac1{2+2x}\left(1-\frac{4x}{2+2x}\right)^{-1/2}\tag6\\
&=\frac1{2-2x}\left(\frac{1-x}{1+x}\right)^{1/2}
+\frac1{2+2x}\left(\frac{1+x}{1-x}\right)^{1/2}\tag7\\[6pt]
&=\left(1-x^2\right)^{-1/2}\tag8\\[6pt]
&=\sum_{n=0}^\infty\frac1{4^n}\binom{2n}{n}x^{2n}\tag9
\end{align}
$$
Explanation:
$(4)$: compute the generating function
$(5)$: apply $(3)$
$(6)$: apply $(2)$
$(7)$: simplify
$(8)$: simplify
$(9)$: apply $(2)$
Equating coefficients of $x^{2n}$ gives $$ \sum_{k=0}^\infty\binom{2k}{k}\binom{2n}{k}\left(-\frac12\right)^k =\frac1{4^n}\binom{2n}{n}\tag{10} $$
On
$2kCk=$ coefficient of $x^k$ in $(1+x)^{2k}$ = constant term in $(\frac{(1+x)^2}{x}^){k}=(x+1/x+2)^k$.
So constant term in $$\sum_{k=0}^{2n} (x+1/x+2)^k {2n \choose k}\left( \frac{-1}{2} \right)^k$$.
$k \rightarrow 2n-k$ and $2nCk=2nC{2n-k}$ (basically writing sequence in reverse order)
$\implies$ Constant term in
$$\sum_{k=0}^{2n} (x+1/x+2)^{2n-k} {2n \choose k}\left( \frac{-1}{2} \right)^{2n-k}$$
$\implies$ Constant term in
$$4^{-n} \sum_{k=0}^{2n} (x+1/x+2)^{2n-k} {2n \choose k}(-2)^{k}$$
By binomial expansion it is constant term in
$$4^{-n} (x+1/x+2-2)^{2n}= 4^{-n}(x+1/x)^{2n} = 4^{-n} \sum_{r=0}^{n} {n \choose r}{n \choose n-r} = 4^{-n} {2n \choose n}$$ by vandermonde's identify.
(the last result follows from selection of the term x, r times (r=0,1,...n) in the expansion implies we need to select to the term 1/x, n-r times for the resulting product to become a constant term).
We use the coefficient of operator $[z^n]$ to denote the coefficient of $z^n$ of a series. Recalling the generating function of the central binomial coefficients we can write \begin{align*} [z^n]\frac{1}{\sqrt{1-4z}}=\binom{2n}{n}\tag{1} \end{align*}
Comment:
In (2) we apply the coefficient of operator according to (1).
In (3) we use the rule $[z^{p-q}]A(z)=[z^p]z^qA(z)$.
In (4) we apply the binomial theorem.
In (5) we write the expression using formal residual by applying again the rule from comment (3).
In (6) we use the substitution $z=\frac{t}{1-t}, dz=\frac{1}{(1-t)^2}dt$.
In (7) we do some simplifications.
In (8) we select the coefficient of $t^{2n}$ by taking (1) evaluated at $z=\frac{1}{4}t^2$.