I am looking at this related rates question and since I haven't worked on these types of problems for a while, I just wanted to check if I have done things right.
I simply derived the function giving me
$$Dv=4kr^3dr$$
And then I input $5$ into $r$ and $-0.1$ into $dr$ and solve for $Dv$? I get $-50mm$ per week as the decrease in volume. Have I dont this right or have I missed something?

What is notable about the data given in this question is that the rate of change for the artery radius has units of mm/week. This implies that both the volume and the radius are functions of time themselves. In your answer you have not used that fact. To do this, we can differentiate with respect to time and invoke the chain rule:
$$V = kr^4 \implies \frac{dV}{dt} = 4kr^3 \frac{dr}{dt} $$
If $r=5$ mm and $\frac{dr}{dt} = - 0.1$ mm/week then $\frac{dV}{dt} = 4k(5)^3(-0.1) = -50k \, \frac{\mathrm{mm^4}}{week}$.
You had the right idea, but your notation could use some more clarifying and you forgot to include $k$ in your answer.
Best of luck.