Sequence of irreducible polynomials

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Does there exist a sequence of nonzero integers $a_n$ such that for all $n$ the polynomial $\sum_{k=0}^n a_k x^k$ is irreducible if:

1) every $a_n$ is prime;

2) all $a_n$ are pair wise coprime;

3) no other conditions?

I heard problem 2 was asked somewhere but I don't know neither answer nor the source.