Show that $Q(x):=200x^3-200x^2+200x+100$ is an irreducible polynomial over the field $\mathbb{Q}$ of rational numbers.

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Show that $Q(x):=200x^3-200x^2+200x+100$ is an irreducible polynomial over the field $\mathbb{Q}$ of rational numbers.

I'm trying to use Eisenstein's Criterion to prove this but I think I don't quite understand the theorem maybe. For example if I let $p=2$ then don't both 2 and 4 divide each coefficient?

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First, you can factor out $100$. Let $$P(x)=2x^3 - 2x^2 + 2x + 1.$$ This is an associate of $Q(x)$, so $Q$ is irreducible if and only if $P$ is irreducible.

Now, either apply the “backwards Eisenstein’s Criterion” to $P$, or if you don’t know the backwards Eisenstein, then either prove it (same proof; check your understanding of the original criterion by proving this one), or look at $$R(x) = x^3P\left(\frac{1}{x}\right)= 2 - 2x + 2x^2 + x^3.$$ Show $R$ is irreducible, and conclude that $P$ must also be irreducible.

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You don't need Eisenstein Criterion, a cubic polynomial is irreducible over $\mathbb Q \iff$ it doesn't have rational roots. Since $P(x) = 100(2x^3-2x^2+2x+1)$, you just have to check $\pm1$ and $\pm \frac{1}{2}$.