Showing some sine's are orthogonal

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How can I show that $$\int_{-M}^M \sin (\pi \frac{x+M}{2M})\sin(n \pi \frac{x+M}{2M}) \text{d} x = 0$$ for $M>0$ and $n>1$.

In my mind there should be a way to use that those sine's are eigenfunctions of the laplacian with dirichlet boundary conditions.

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We assume that $n \geq 2$.

Make the change of variable $x=Mu$. We have now to establish that

$$\int_{-1}^1 \sin (\pi\frac{u}{2} + \frac{\pi}{2})\sin(n\pi\frac{u}{2} + n\frac{\pi}{2}) \text{d}u = 0$$

which is equivalent to show that, up to unimportant factors:

$$\int_{-1}^1 \cos (\pi \frac{u}{2})\begin{cases}\cos(n \pi \frac{u}{2}) \text{if n odd}\\\sin(n \pi \frac{u}{2}) \text{if n even} \end{cases} \text{d}u = 0$$

The second case is immediate (integration of an odd function on a symmetrical interval with respect to the origin).

For the first case, use relationship:

$$\cos(u)\cos(v)=\tfrac12(\cos(u+v)+\cos(u-v))$$

Up to you...

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Hint: $\sin A \sin B=\frac 1 2 [\sin (A+B)-\sin (A-B)]$ so it is easy to evaluate the integral explicitly. Finally use the fact that $\cos $ has period $2\pi$.