Having infinitely many open sets in a topology is a topological property
#1: What are example of two topological spaces, preferably simple ones, which this statement show are not homeomorphic.
But, more importantly why does it show this? Having trouble understanding topological properties in connection to homeomorphisms.
#2: What about two spaces where this statement doesn't help deciding whether they are homeomorphic or not?
Let $X$ be a point and $Y$ the integers, both with the discrete topology. Then $X$ has finitely many open sets, while $Y$ has infinitely many open sets. But since there's no bijection between the two, they definitely can't be homeomorphic.
Topological properties are the same as invariants under homeomorphism. Checking for different topological properties can tell you when spaces are not homeomorphic.