Structures created from cell complexes

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I've recently started stydying algebraic topology and am now learning about cell complexes. I understand the iterative construction of such spaces, but I lack any intuition concerning the limitations on the possible resulting structures.

I thus have two questions for which I am seeking, preferably, non-highly technical answers:

1) What types of structures can, and cannot, be created iteratively from cells?

2) What types of spaces are, and are not, homotopic to the spaces created from cells?