If $D$ is an integral domain containing an irreducible element, then $D[x]$ is not a principal ideal domain.
If $F$ is a field and $n \ge 2$, then $F[x_1,...,x_n]$ is not a principal ideal domain. [Hint: show that $x_1$ is irreducible in $F[x_1,...,x_{n-1}]$.
I have already worked on part 1, but I am having trouble proving what the hint in part 2. suggests. I imagine the statement is to be proven through induction. Here is my proof of the base case. Suppose that $x =pq$ for $p,q \in F[x]$. Then $1 =\deg(pq) = \deg(p) + \deg (q)$, which implies, WLOG, that $p = ax + b$ and $q = c$, where $a,b,c \in F$ and $c \neq 0$. Then $x = pq = acx + bc$ implies $ac=1$ and $bc=0$. Since $c \neq 0$, it must be that $b=0$, and $a$ and $c = q$ are units. Hence, $x$ is irreducible.
The inductive step is giving me a little more trouble. Suppose that $x_1$ is irreducible in $F[x_1,...,x_{n-1}]$, and suppose that $x_1 = pq$ for $p,q \in F[x_1,..,x_n]=(F[x_1,...,x_{n-1}])[x_n]= D[x_n]$ (strictly speaking, I think this is an isomorphism). Note that $x_1$ as a constant in $D[x_n]$, so that $0=\deg(x_1) = \deg(pq)= \deg(p)+\deg(q)$ implies $p = f(x_1,...,x_{n-1})$ and $q=g(x_1,...,x_{n-1})$ are constants. In particular, they satisfy $1 = fg$ and so are units in $D=F[x_1,...,x_{n-1}]$......
Isn't it true that the units of $D[x_n]$ will be the units of $D$? If so, can I conclude that $p$ and $q$ are units in $D[x_n]$ and then conclude that $x_1$ is irreducible in $F[x_1,...,x_n]$? Is that right? Obviously proving 2. is trivial at this point: $F[x_1,...,x_{n-1}]$ contains the irreducible element $x_1$, and so by part 1. $F[x_1,...,x_n]$ cannot be a PID.
Hint:
For step 2, you don't need really induction. You just have to prove this: