While fitting a Gaussian distribution to another Gaussian, I came up with this term
$$\mbox{trace} (\Sigma^{\frac{1}{2}} S^{-1}\Sigma^{\frac{1}{2}})$$
I need to compute its derivative with respect to $\Sigma$. Both $\Sigma$ and $S$ are positive definite matrices.
The trace of product is invariant under cyclic permutations of the product. Thus
$\mbox{tr}(\Sigma^{1/2}S^{-1}\Sigma^{1/2})=\mbox{tr}(\Sigma^{1/2}\Sigma^{1/2}S^{-1})=\mbox{tr}(\Sigma S^{-1})$
The derivative of $\mbox{tr}(\Sigma S^{-1})$ with respect to $\Sigma$ is $S^{-1}$.