Which distribution to use

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After many generations, it is known that 75% of students pass certain subject. if a random sample of 40 students is such that it could be consider they have the same characteristics as the ones observed. ¿Which is the probability that at least 50% of them pass the subject?

I would say that $X\sim Bernoulli(.75)$, also I would like to use Central Limit Theorem or any other distribution to approximate the probability of the 40 student sample. Can you help me?

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You are right. You could model each student's success as a Bernoulli random variable with $p = 0.75$ probability of success.

Also, embedding the CLT here sounds like a good approximation because it seems exhaustive to compute the following probability $$Pr( \sum_{i=1}^{40} X_i \geq 20)$$ where $X_i \sim B(0.75)$. Equivalently, we can say (dividing $40$ on both sides) $$Pr( S_{40} \geq 0.5)$$ where $$S_{40} = \frac{\sum_{i=1}^{40} X_i}{40}$$ The CLT tells you that if $X_1 \ldots X_{40}$ are i.i.d (which is your case), then $$\sqrt{40}(S_{40} - \mu) \rightarrow \mathcal{N}(0,\sigma^2)$$ where \begin{align} \mu &= E(X) = p = 0.75 \\ \sigma^2 &= \operatorname{var}(X) = p(1-p) = 0.75(0.25) = \frac{3}{8} \\ \end{align} Hence, we get $$\sqrt{40}(S_{40} - 0.75) \rightarrow \mathcal{N}(0,\frac{3}{8})$$ You could choose to standardize as such $$Z = \frac{S_{40} - 0.75}{\frac{\frac{3}{8}}{\sqrt{40}}} \sim \mathcal{N}(0,1)$$ Going back to your probability $$Pr( S_{40} \geq 0.5)$$ All you have to do is standardize now, i.e. $$ Pr(\frac{S_{40} - 0.75}{\frac{\frac{3}{8}}{\sqrt{40}}}\geq \frac{20 - 0.75}{\frac{\frac{3}{8}}{\sqrt{40}}}) = Pr (Z \geq \frac{20 - 0.75}{\frac{\frac{3}{8}}{\sqrt{40}}})$$ and this is the Normal Approximation of the Binomial Distribution.