Today is Mardi Gras, so I decided to try to connect two of my friend's drawer handles together with a necklace.
It is easy to connect the necklace to one drawer handle. (See picture for what I mean by "connect.")
However, at this stage I am unable to connect the necklace to a second drawer handle. Is this impossible? My thinking is that the necklace and the two handles represent a total of 3 loops in $\mathbb R^3$. If you can connect two of these loops together, why can't you do the same procedure to connect the third one? Would the resulting configuration be a nontrivial link?

If you had three loops in $\mathbb{R}^{3}$ (ignoring the middle handle) that you could move around then you could tie the necklace (one of the loops) to the other two in the way you want. That is, the resulting link is still trivial. This can be seen by "unlooping" the middle loop of the diagram below:
However, if two of your loops are fixed I believe that it is not possible.
If you want to tie up your comrade's desk you can do it in the way you described. You will simply need a much longer necklace and will have to pull out the drawers.
I do not know if it is against MSE rules to encourage you to do this, but I expect that you will make us proud.
Here's how you do it: