If you ever heard about Collatz conjecture, you know that it is understandable even for middle school students, but no one has solved it yet. The problem is to prove or to disprove that starting with any natural number $a_0$ and going $a_{n+1} = f(a_n)$, eventually you will always get $a_m = 1$ for some $m$.
$$ f(n)=\begin{cases}n/2&{\text{if }}n\equiv 0{\pmod {2}}\\(3n+1)/2&{\text{if }}n\equiv 1{\pmod {2}}.\end{cases} $$
There a lot of other "simple" problems in mathematics that are still unsolved. For example, Goldbach's conjecture that states:
Every even integer greater than 2 can be expressed as the sum of two primes.
Do you have any intuitive explanation as to why modern advanced mathematics cannot solve such seemingly simple problems?
Simple to state, could also mean too many trivial conditions to easily hit a contradiction. That makes it hard to disprove, but combined with abnormal use of defined objects, it makes it nearly impossible until we find more theory.
You can change a conjecture into collaries, or necessary conditions, etc. , but that doesn't easily let us induce it necessarily.
A necessary condition in itself, is not usually a sufficient condition. It takes a big enough set of them to ensnare the problem.
One condition on Collatz is that any nontrivial cycle has a lowest element, with an odd number of prime factors of form $4k+3$ when counted with multiplicity if odd.
You can partially induce Goldbach, via Collatz map and https://oeis.org/A158709 but only partially. Even if the sequence is infinite.
Our two main proof types currently seem implausible to reach a conclusion.