Why unit circle is not diffeomorphic to the real line

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I read from a text book that unit circle ($\mathbb{S}$) is not diffeomorphic to the real line. This result is intuitive since we cannot construct a smooth function from $\mathbb{S}$ to $\mathbb{R}$ such that it is onto (e.g., $f(\rho)=(\cos(\rho),\sin(\rho))$ defined from $\mathbb{R}$ to $\mathbb{S}$ is not onto). How can I prove this result?

Incidentally, I am not familiar with advanced topics in topology. Thank you, in advance, for your response!

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The two sets, the unit circle and the real line are not even homeomorphic.

Note that removing a point from the real line makes it disconnected but removing a point form the unit circle keeps it connected.