Let $\mathcal A$ be an abelian category. Let $\mathbb K(\mathcal A)$ be the homotopy category of complexes of $\mathcal A$. Now. consider a functor $F$ from $\mathbb K(\mathcal A)$ to $\mathbb E$, which is also a triangulated category. Suppose the $F$ takes quasi-isomorphisms to isomorphisms. Now by the universal property of $\mathbb D(\mathcal A)$, the derived category of $\mathcal A$, we know there is a functor $F'$ from $\mathbb D(\mathcal A)$ to $\mathbb E$ induced by functor $F$.
Is $F'$ a triangulated functor?
By triangulated functor, I mean a functor which commutes with the translation functor and takes distinguished triangles to distinguished triangles.
Edit: In this answer, I assume that the functor $F$ is triangulated. The answer is different in case $F$ is not, as explained in Jeremy Rickard's answer.
Yes, $F'$ is a triangulated functor.
One way to formulate this is by saying that the derived category is the triangulated quotient of $\mathbb{K}(\mathcal{A})$ by the full subcategory of objects with vanishing total homology. The universal property of a triangulated quotient then gives the property you want, since any functor $F$ that takes quasi-isomorphisms to true isomorphisms will take objects with vanishing homology to zero.