A field $\mathbb{K}$ is said to be algebraically closed in practice if every polynomial over $\mathbb{K}$ of positive degree less than or equal to $10^{10}$ has zero belonging $\mathbb{K}$. The question arises: is it possible that an algebraically closed in practice field is not algebraically closed?
PS. The question still remains open in characteristic 0.
Let me expand on Dustan Levenstein's answer in the comments: inside the algebraic closure $\overline{\mathbb{F}_p}$ of $\mathbb{F}_p$, consider the union $K = \bigcup_i \mathbb{F}_{p^{(N!)^i}}$, for $N = 10^{10}$. Since this is a nested union, $K$ is a field. If $f(x) \in K[x]$ is a polynomial of degree $\le 10^{10}$, then $f(x) \in \mathbb{F}_{p^{(N!)^i}}[x]$ for some $i$ (since $f$ has finitely many coefficients). Setting $q = p^{(N!)^i}$, we have that $f(x) \in \mathbb{F}_q[x]$ has an irreducible factor of degree $\le 10^{10}$, and thus splits in $\mathbb{F}_{q^(N!)} = \mathbb{F}_{p^{(N!)^{i+1}}} \subseteq K$.
However, $K$ is not algebraically closed - if $q > N!$ is prime, then $\mathbb{F}_{p^q} \not \subseteq K$. If it were, then $\mathbb{F}_{p^q} \subseteq \mathbb{F}_{p^{(N!)^i}}$ for some $i$ (since $\mathbb{F}_{p^q}$ is a finite field), but $\mathbb{F}_{p^d} \subseteq \mathbb{F}_{p^e}$ iff $d \mid e$.