Let $\{a_j\}$ be an arithmetic sequence with the following conditions:
Given $s_{16} = 376$ and $a_{16} = 46$, find $a_1$.
$$s_n = \frac{n}{2} \cdot(a_1 + a_n) $$
$376 = \dfrac{16}{2} \cdot (a_1 + 46)$
$47 - 46 = 1$
$a_1 = 1$
common ratio $= -5$?
Don't need that value however.
Your approach is correct, but it would be better to write it something like $$376=\frac {16}2(a_1+46)\\\frac {376}8=a_1+46\\1=a_1$$ Your statement that $47-46=1$ is correct, but is not motivated. This is why we keep the variables in the equations.
The difference (not common ratio) is $5$, not $-5$ as the terms are increasing.