$\newcommand{\Hom}{\operatorname{Hom}}$Any category is equipped with a covariant hom-functor $\Hom(A,-)$, by letting the second argument vary. The covariant Yoneda lemma says $\operatorname{Nat}(\Hom(A,-),F)\cong F(A)$ for any covariant functor $F$.
Alternatively any category is equipped with a contravariant hom-functor, by instead letting the first argument vary. Then for contravariant functors $F\colon C^\mathrm{op}\to \operatorname{Set},$ we have the contravariant Yoneda lemma $\operatorname{Nat}(\Hom(-,X),F)\cong F(X).$
Instead of choosing one or the other argument to vary, we may let both vary. Giving the hom functor as a bivariate functor $\operatorname{Hom}(-,-)\colon C^\mathrm{op}\times C\to \operatorname{Set}$. Is there a Yoneda lemma for this functor as well?
Show that $\mathsf{Nat}(\mathsf{Hom}(-_1,X)\times\mathsf{Hom}(A,-_2),P)\cong P(A,X)$ where $P:\mathcal C^{op}\times\mathcal C\to\mathbf{Set}$. You can prove this by currying and applying each variation of the Yoneda lemma. Or, you can realize that the two variants of the Yoneda lemma are the same statement, and the above is also just a special case of the Yoneda lemma.