Calculate if a number has changed "radically"

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Trying to apply math to a computer program problem: I want to find out if the size of a text file has changed "radically" compared to the last X successfully processed files. So far I have calculated the standard deviation from the last 20 files size in bytes, but not sure how to proceed and apply that number on the file size (yeah my 9th grade math is somewhat cloudy!).

How should I calculate this?