The problem is: $$ \int { (x+1)({ x }^{ 2 } } +2x{ ) }^{ 5 }dx $$
The next step given by WolframAlpha is $$\int { (x+1)({ x }^{ 2 } } +2x{ ) }^{ 5 }dx\\ =\quad \frac { 1 }{ 2 } \int { { u }^{ 5 }du } $$
(While I realize I am doing somthing worng)
The steps I am taking are : $ \int { (x+1)({ x }^{ 2 } } +2x{ ) }^{ 5 }dx$.
Let $u={ x }^{ 2 }+2x, \, du = 2x+2\, dx$. Then I see I can rewrite $du$ as $du = 2(x+1)dx$ giving me $\frac { du }{ 2 } = (x+1)\, dx$.
I can now see where the $ \frac { 1 }{ 2 } $ is coming from, but I cannot seem to visualize the next steps to get to
$$ \int { (x+1)({ x }^{ 2 } } +2x{ ) }^{ 5 }dx=\frac { 1 }{ 2 } \int { { u }^{ 5 }du } $$
You already state in your question that you found that $$\frac{\mathrm{d}u}{2} = (x+1)\mathrm{d}x$$
when doing the substitution $u=x^2+2x$. When doing this substitutiuon on the integral, we get $$\int (x+1)(x^2+2x)^5 \mathrm{d}x = \int (x+1)u^5 \mathrm{d}x = \int u^5 (x+1)\mathrm{d}x = \int u^5 \frac{\mathrm{d}u}{2} = \frac{1}{2} \int u^5 \mathrm{d}u$$