Let $\mathcal{F}$ be nonzero coherent sheaf over the projective space $\mathbb{P}_k^n$. The Serre vanishing Theorem says that $h^i \mathcal{F}(d)=0$ for $i>0$ and $d\gg 0$.
I am wondering if it is always true that $h^0 \mathcal{F}(d) \neq 0$ for $d \gg 0$, and if itn't, under which conditions can that be true.
In the same context, can we say that $h^n \mathcal{F}(d) \neq 0$ for $d \ll 0$? and if not, under which conditions can that be true.
Thank you.
Just to have this down as an answer.
Yes, such a $d$ does exist. Note since $\mathcal{O}(1)$ (the canonical very ample bundle on $\mathbb{P}^n$) is ample, we know that there exists $d\geqslant 0$ such that $\mathcal{F}\otimes\mathcal{O}(d)$ is globally generated. Suppose that $h^0(\mathcal{F}\otimes\mathcal{O}(d))=0$. Then, by the fact that $\mathcal{F}\otimes\mathcal{O}(d)$ is globally generated, we would have that $(\mathcal{F}\otimes\mathcal{O}(d))_p=0$ for all $p\in\mathbb{P}^n$. Thus, $\mathcal{F}\otimes\mathcal{O}(d)=0$, and so
$$\mathcal{F}=(\mathcal{F}\otimes\mathcal{O}(d))\otimes\mathcal{O}(-d)=0$$
contradictory to assumption. So, $\mathcal{F}\otimes\mathcal{O}(d)$ has non-zero global sections.
Now, we also want to show that there is $d\ll 0$ such that $h^n(\mathcal{F}\otimes\mathcal{O}(d))\ne 0$. But, for any $d\leqslant 0$, we have that
$$H^n(\mathbb{P}^n,\mathcal{F}\otimes\mathcal{O}(d))\cong H^0(\mathbb{P}^n,(\mathcal{F}\otimes\mathcal{O}(d))^\vee\otimes\mathcal{O}(-n-1))^\vee$$ by Serre duality (since $\omega_{\mathbb{P}^n}=\mathcal{O}(-n-1)$). Since $\mathcal{O}(d)$ is a line bundle, we have an isomorphism
$$(\mathcal{F}\otimes\mathcal{O}(d))^\vee\cong \mathcal{F}^\vee\otimes\mathcal{O}(-d)$$
and so
$$H^n(\mathbb{P}^n,\mathcal{F}\otimes\mathcal{O}(d))\cong H^0(\mathbb{P}^n,\mathcal{F}^\vee\otimes\mathcal{O}(-d-n-1))^\vee$$
Since $\mathcal{F}^\vee$ is still coherent, the first part shows that for $d\ll 0$, this right hand side will be non-zero, as desired.