In this question we are only interested in convex polyhedra in the Euclidean space $\mathbb R^3$.
Polyhedra $P$ and $P'$ are said to be combinatorially equivalent iff there is a bijection between them (denoted here as $X\mapsto X'$) preserving the number of vertices, edges and faces and their relations (i.e. edge $E$ connects vertices $A$ and $B$ and separates faces $G$ and $H$ in $P$ iff edge $E'$ connects vertices $A'$ and $B'$ and separates faces $G'$ and $H'$ in $P'$). Note that we ignore possible chirality, and thus every polyhedron is combinatorially equivalent to its mirror image.
Recall that a subset $S$ of $\mathbb R^3$ is dense iff there is a point from $S$ in every neighborhood of every point of $\mathbb R^3$. For example, the set of all points with rational coordinates is dense.
Question: Is it true that for every dense subset $S$ and every polyhedron $P$ there is a combinatorially equivalent polyhedron whose all vertices belong to $S$?
Your comment guided me onto the right track.
Claim. There is a dense subset $S \subseteq \mathbb R^3$ that doesn't contain $4$ distinct, coplanar points.
Proof. Fix a countable basis $\mathcal B = \{ O_n \mid n \in \mathbb N \}$ for the topology of $\mathbb R^3$ not containing $\emptyset$ as an element. We recursively construct a sequence $(S_n \mid n \in \mathbb N_0)$ such that for all $m,n \in \mathbb N_0$ with $m < n$
If we manage to construct such a sequence, then $S = \bigcup \{ S_n \mid n \in \mathbb N_0 \}$ is countable, dense and doesn't contain $4$ distinct coplanar points. Towards this end let $S_0$ be any set of $4$ points that are not coplanar and such that no $3$ points of $S_0$ are colinear (e.g. $S_0 = \{(0,0,0), (1,0,0), (0,1,0), (0,0,1) \}$).
Given $S_n$ let $[S_n]^3$ be the set of all subsets of $S_n$ that contain precisely $3$ distinct points. Since no $3$ points of $S_n$ are colinear, any $s \in [S_n]^3$ spans a two dimensional, affine subspace of $\mathbb R^3$ which we denote by $P_s$. Let $[S_n]^2$ be the set of all subset of $S_n$ that contain precisely $2$ distinct points. For each $s \in [S_n]^2$ let $L_s$ be the affine line spanned by $s$. Let $X = \bigcup \{ P_s \mid s \in [S_n]^3 \} \cup \bigcup \{ L_s \mid s \in [S_n]^2 \}$. Since $X$ is a finite union of sets with Lebesgue measure $0$, we know that $X$ has Lebesgue measure $0$. In particular, this yields $O_n \setminus X \neq \emptyset$. Choosing some $s_n \in O_n \setminus X$, we let $S_{n+1} = S_n \cup \{s_n\}$. $\square$
If $S$ is as in the claim, there is no polyhedra with vertices in $S$ that is combinatorially equivalent to the 'unit cube'. So your question indeed has a negative answer - contrary to my initial instinct.