Let $X_1,\cdots,X_n$ be i.i.d Poisson random variables with mean $\mu$. Let $S=X_1+X_2+ \dots + X_n$. Set $Y=\mathbf{1}[X_1=0]$. Show that $$\mathbb{E}(Y\mid S)=\left(1-\frac{1}{n}\right)^S$$
$$\mathbb{E}(Y\mid S) = \sum y \frac{P(Y,S)}{P(S)}$$
$S$ is of course Poisson with mean $\mu n$. I am stuck here.
Since $Y$ is just an indicator variable,
\begin{align} E(Y\mid S=s)&=P(X_1=0\mid S=s) \\&=\frac{P(X_1=0,S=s)}{P(S=s)} \\&=\frac{P\left(X_1=0,\sum_{i=2}^nX_i=s\right)}{P(S=s)} \\&=\frac{P(X_1=0)P\left(\sum_{i=2}^nX_i=s\right)}{P\left(\sum_{i=1}^nX_i=s\right)} \end{align}
You know that $\sum_{i=1}^n X_i\sim\mathcal P(n\mu)$ due to independence of $X_1,X_2,\cdots,X_n$.
It follows on simplification that $$E(Y\mid S=s)=\left(1-\frac{1}{n}\right)^s$$
If we are estimating the unknown parameter $μ$, then this conditional expectation indeed gives us the UMVUE of $P(X_1=0)=e^{−\mu}$.