Consider the function $f(x) = 1/x$ on the interval $I = [a, b]$, where $0 < a \leq b$. By Jensen's inequality, we have for any $\{x_j \}_{j=1}^n \subset I$,
$$ f(\overline{x}) \leq \frac{1}{n} \sum_{i=1}^n f(x_i). $$
Above, $\overline{x} = (1/n)\sum_{j=1}^n x_j$. Is there a converse inequality of the form $$ \frac{1}{n} \sum_{i=1}^n f(x_i) \leq C f\Big(\frac{1}{n}\sum_{i=1}^n x_i\Big), $$ where $C$ may depend on $a, b$?
One thing I thought of is a second-order Taylor expansion. By Taylor expansion, there are $\xi_i$ in the interval between $x_i, \overline{x}$ such that $$ \frac{1}{n} \sum_i f(x_i) = f(\overline{x}) + \frac{1}{2n} \sum_{i=1}^n f''(\xi_i) (x_i - \overline{x})^2. $$ Additionally, we have that $f''(\xi) = \tfrac{2}{\xi^3}$, so that the remainder is $$ \frac{1}{n} \sum_{i=1}^n \frac{(x_i - \overline{x})^2}{\xi_i^3} \leq \frac{1}{n} \sum_{i=1}^n \max \Big\{ \frac{(x_i - \overline{x})^2}{x_i^3}, \frac{(x_i - \overline{x})^2}{\overline{x}^3} \Big\}. $$ I struggled to bound this remainder in terms of $C(a, b)~f(\overline{x})$, though.
$C = \frac{(a+b)^2}{4ab}$ is an upper bound for the ratio, and that bound is best possible.
Proof: If $a_1, \ldots, a_n$ and $b_1, \ldots, b_n$ are real numbers in the interval $[m, M]$, $0 < m < M$, then $$ \sum_{k=1}^na_k^2\sum_{k=1}^nb_k^2 \le \left(\dfrac{M+m}{2\sqrt{Mm}}\sum_{k=1}^n a_kb_k\right)^2 \, . $$ This is a discrete version of a Pólya-Szegő inequality, see for example Reverse Cauchy Schwarz for integrals.
We can apply this with $a_k = \sqrt {x_k}$, $b_k = 1/\sqrt{x_k}$, $[m,M] = [a, b]$. It follows that $$ \sum_{k=1}^n x_k\sum_{k=1}^n \frac{1}{x_k} \le n^2 \frac{(a+b)^2}{4ab} $$ and therefore $$ \frac 1n \sum_{k=1}^n f(x_k) \le \frac{(a+b)^2}{4ab} f\left( \frac 1 n \sum_{k=1}^n x_k\right) \, . $$
The bound is best possible: If $n$ is even then equality holds if half of the $x_k$ are equal to $a$ and the other half are equal to $b$. If $n$ is odd then asymptotic equality holds if $(n-1)/2$ of the $x_k$ are equal to $a$ and $(n+1)/2$ of the $x_k$ are equal to $b$.