There are numerous explanations of converting an $n^\text{th}$ order differential equation
$$\sum_{i=0}^n a_i \frac{\partial^i x}{\partial t^i} = 0 $$
to a linear system with $n$ dimensions.
$$\frac{d \underline{x}}{dt} = \mathrm{A}\underline{x}$$
Can I perform the reverse operation and convert an arbitrary linear system back to an ode?
Obviously it is trivial to possible to perform the reverse operation when $\mathrm{A}$ has the $\begin{bmatrix}\underline{\alpha} & \beta \\ \mathrm{I} & \underline{0} \end{bmatrix}$ structure resulting from the forward operation, but my only progress for general $\mathrm{A}$ is that it is an equivalent problem to using the diagonal matrix $\Lambda$ by eigendecomposition and change of variables
$$ \frac{d \underline{u}}{dt} = \Lambda \underline{u}, \qquad \mathrm{A} = Q^{-1}\Lambda Q ,\qquad \underline{u} = Q \underline{x}$$
Consider the linear state system
$$\dot{x}(t) = A\,x(t) + B\,u(t)$$
$B\,u(t)$ is zero in your case. It is a time-dependent input, such as a force on a mass-spring-damper system. I'm just putting it there as it is a valid term in a linear set of equations, with the purpose of obtaining a general solution.
We can write
$$S\,I\,x(t) = A\,x(t) + B\,u(t)$$
where $S$ is the differential operator $\textrm{d}/\textrm{d}t$ and $I$ an identity matrix. Assuming that $(S\,I - A)$ is invertible (which it is unless you have two independent state systems into a single set) we can write
$$x(t) = (S\,I - A)^{-1}B\,u(t) \to \det{(S\,I - A)}\,x(t) = \mathrm{adj}\,{(S\,I - A)} B\,u(t) $$
which will give you your $n$th order differential equation. In your case, $B\,u(t)=0$, so you'll find your solution by computing $\det{(S\,I - A)}\,x(t)=0$.