Does every uncountable topological space has a different and mutually "countably close" space?
Define "countably close" space $S$ with respect to another space $S'$ both on the same set iff the difference between any open set $U\in S$ and some open set $V\in S'$ is countable $|U\setminus V|\leq\aleph_0$
I tried disproving the negation by taking some space and some open set from any other so that their difference is uncountable but still couldn't get it.
The cocountable topology provides a counter-example. In this topology a set is open iff it is cocountable, i.e., its complement is countable. Removing a countable set from a cocountable subset of an uncountable set gives you a cocountable set, so a topology that is countably close to the cocountable topology must be the same as the cocountable topology.
[EDIT] The above was based on a possible misunderstanding that $V \subseteq U$ was required in the original question. I will revisit the answer.