I am wondering this. Suppose I have a sequence $\{\varepsilon_n\}_{n=0}^\infty$ and elements of this sequence are part of a binomial type expression: For example, my expression is $$\sum_{k=0}^n\binom{n}{k}\varepsilon_k2^{n-k}$$
If I knew, for example that the expresssion was equal to 1, then I would know that $\varepsilon_n=(-1)^n$ because
$$\sum_{k=0}^n\binom{n}{k}\varepsilon_k2^{n-k}=1=1^n=[2+(-1)]^n=\sum_{k=0}^n\binom{n}{k}(-1)^k2^{n-k}$$
I'm almost sure that the answer is "no" but here it is. Is there any way to simplify an expression like mine as
$$(2+x)^n=\sum_{k=0}^n\binom{n}{k}\varepsilon_k2^{n-k}$$ when the terms in the expansion are not constants such as $x$ raised to powers but corresponding elements indexed appropriately?
If I knew, for example that the expresssion was equal to $1$, then I would know that $\varepsilon_n=(-1)^n$ because \begin{align*} \sum_{k=0}^n\binom{n}{k}\varepsilon_k2^{n-k}=1=1^n=[2+(-1)]^n=\sum_{k=0}^n\binom{n}{k}(-1)^k2^{n-k}\tag{1} \end{align*}
Conclusion: A simplification of the sum (3) in the general case (arbitrary $\varepsilon_k, 0\leq k \leq n-1$) is not achievable.