Four dice are rolled SIMULTANEOUSLY. $X_1$ is a random variable that represents how many 1's you get in a single roll. $X_2, ... , X_4$ are defined in the same fashion, like in the picture below. 
Remember the rolls are NOT consecutive. Let Y = $X_1X_2X_3X_4$. What values Y can get? Get $E(Y)$
$Y$ takes the values $0$ and $1$, the latter if and only if you have one each of $1,2,3$ and $4$, which occurs with probability $4!/6^4=1/54$, which is thus the value of $E(Y)$.