Let $F(a,b,c) = \iiint\limits_{V}f(x,y,z,a,b,c) dx\ dy\ dz$,
V = $\{(x,y,z)| \ ... \}$ a connected, bounded and closed domain in $R^3$,
and $B((0,0,0),r))$ a ball in $R^3$ as a domain for $(a,b,c)$.
Under the assumption that $f$ and $\frac{\partial f}{\partial a}$ for instance are continuous for $(x,y,z) \in V$ and $(a,b,c) \in B$
is it possible to claim that:
$\frac{\partial}{\partial a}F(a,b,c) = \frac{\partial}{\partial a} \iiint\limits_{V}f(x,y,z,a,b,c) dx\ dy\ dz = \iiint\limits_{V} \frac{\partial}{\partial a}f(x,y,z,a,b,c) dx\ dy\ dz $ ?
If you assume $f$ and $\dfrac{\partial f}{\partial a}$ are continuous as "a function of $6$ variables" $(x,y,z,a,b,c) \in V \times B$, then yes, the result is true, and the proof is pretty easy; it uses the fact that continuous functions on compact sets are uniformly continuous. Below, I present a statement which is valid in higher dimensions. You could probably get away with weaker hypotheses, but the version I'm stating is valid for many applications (at least the ones I've come across), and it is pretty easy to prove; the key ingredients are the (single-variable) mean-value theorem (for derivatives) and the fact that continuous fucntions on compact sets are uniformly continuous.
A few points to note are the following: