Consider an arrangement of finitely-many open polygons in the plane (not necessarily convex) such that each polygon intersects at least two other non-intersecting polygons.
Is there always a sub-arrangement such that the union of all polygons in the sub-arrangement contains a hole?
In the illustration below, the blue arrangement on the left satisfies the requirements and indeed it contains a hole; the brown arrangement on the right does not satisfy the requirements (each polygon intersects two other polygons, but these other polygons intersect), and it does not contain a hole.

Note
The answer above was given to the question in its first revision.
Subsequent edits added explicit requirement for the sets in question to be closed first, and then to be open, which rendered the answer irrelevant.
This looks like a chase, so fixing an answer doesn't make sense.
I restored it to its initial shape and do not care about it any more.