Equation to oxygen diffusion on the sphere

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I am reading the book The Mathematics of Diffusion by J. Crank (cf. Crank_1975_Diffusion) and, at page 89, I could not understand the equation of radial diffusion:

$$\dfrac{\partial C}{\partial t}=D\bigg(\dfrac{\partial^2C}{\partial r^2}+\boxed{\dfrac{2}{r}\dfrac{\partial C}{\partial r}}\bigg).$$

What is the physical meaning of the boxed term?

Many thanks in advance.

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The diffusion equation is

$$ \frac{\partial C}{\partial t}=D\Delta C\;. $$

The boxed term arises from expressing the Laplacian $\Delta C$ of a radially symmetric function $C$ in spherical coordinates; you can derive it from the more symmetric expression $\frac1{r^2}\frac\partial{\partial r}\left(r^2\frac{\partial C}{\partial r}\right)$ by carrying out the outer differentiation. See Wikipedia here and here.