"Can you to any uncountably infinite set $M$ find an uncountably infinite family $F$ consisting of pairwise disjoint uncountably infinite subsets of $M$?"
Intuitively, I feel like it should be possible for the real numbers at least: you simply split the real numbers into two intervals, and since there are uncountably many points where you can do that, there are uncountably many ways to split the reals into two disjoint subsets. But this question isn't asking specifically about the real numbers, so how can I prove this more generally?
Your approach does not work even for $\Bbb R$: you’ve merely shown that there are uncountably many different ways to split $\Bbb R$ into two disjoint uncountable sets. Your task is to split $M$ into uncountably many pairwise disjoint uncountable sets.
HINT: $|M\times M|=|M|$ (assuming the axiom of choice).