My brother wants to take a sign to the Sign Post Forest in Canada's Yukon. He wants it to show the distance to London, but directly through a tunnel that only exists in his head. There's not a lot in his head. So it's the mathematically shortest possible distance through the Earth between the Sign Post Forest and the flag pole on Buckingham Palace.
The two locations are here, obtained from Google Maps:-
There's a whole load of "Similar Questions" coming up on my screen, but none seem to calculate the direct distance via a hypothetical tunnel. They're all on the surface. It seems that the size of the Earth is needed, and I found some parameters for it from this GPS /WGS84 document:-
equatorial radius (WGS84)- 6378137 m
polar radius (derived) - 6356752.3 m


For future reference, the most accurate method to perform this type of calculation is by using an ellipsoidal Earth model, starting with the geographic coordinates (latitudes, longitudes and ellipsoidal heights $\phi, \lambda, h$) of your points, transforming them to cartesian (X, Y, Z) coordinates, then calculating the 3D distance with the Pythagorean theorem. Spherical trigonometry is an approximation that, although good, can give errors up to about 0.5% for Earth coordinates.
The formulas to convert geographic coordinates to cartesian are:
$$X = \left(N\left(\phi\right)+h\right)\text{cos }\phi\text{ cos }\lambda$$ $$Y = \left(N\left(\phi\right)+h\right)\text{cos }\phi\text{ sin }\lambda$$ $$Z = \left(\frac{b^2}{a^2}N\left(\phi\right)+h\right)\text{ sin }\phi$$ Where $$N\left(\phi\right)=\frac{a}{\sqrt{1-e^2\text{ sin}^2\phi}}$$ $$e^2=1-\frac{b^2}{a^2}$$ $$a=6378137\text{ m (in WGS84)}$$ $$b=6356752.314\text{ m (in WGS84)}$$
Then we can find the distance in 3D between the 2 points with the Pythagorean theorem: $$d = \sqrt{(X_2-X_1)^2 + (Y_2-Y_1)^2 + (Z_2-Z_1)^2}$$
We can also find the orientation (zenith angle and geographical azimuth $\theta, \alpha$) of the 2nd point in the 1st point's local reference frame with the following rotation matrix and spherical coordinate conversion: $$\left[\begin{matrix} x \\ y \\ z \end{matrix}\right]=\left[\begin{matrix} -\text{ sin }\lambda_1 & \text{ cos }\lambda_1 & 0 \\ -\text{ sin }\phi_1 \text{ cos }\lambda_1 & -\text{ sin }\phi_1 \text{ sin }\lambda_1 & \text{ cos }\phi_1 \\ \text{ cos }\phi_1 \text{ cos }\lambda_1 & \text{ cos }\phi_1 \text{ sin }\lambda_1 & \text{ sin }\phi_1 \end{matrix}\right]\left[\begin{matrix} X_2-X_1 \\ Y_2-Y_1 \\ Z_2-Z_1 \end{matrix}\right]$$ $$\theta = \text{acos }\frac{z}{\sqrt{x^2+y^2+z^2}}$$ $$\alpha = \text{atan2 }(x,y)$$ Note that the x and y axes are reversed relative to the mathematical couterclockwise polar coordinate system in the atan2 function, since geographical azimuths are calculated clockwise from the North.
For your specific points with geographic coordinates 1(60.063229°, -128.713104°, 699 m) and 2(51.501326°, -0.141968°, 74 m), we find the following answers : $$d=6491.075 \text{ km}$$ $$\theta=120.5066°$$ $$\alpha=33.7938°$$