Hom-like functor to a topos other than Set?

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The hom-set functor is often given as the bifunctor:

$$ \mathbf{Hom}(-,-) : \cal C^{op} \times \cal C \to \mathbf{Set}$$

(This is of course under the assumption that $\cal C$ is locally small.)

Is there a precedent for using a topos other than $\mathbf{Set}$? Such as for instance the category of weak infinity/omega groupoids known from Homotopy Type Theory?