I'm not an expert in MATLAB. Can I use MATLAB function fminimax to solve the problem below?
Let's say I have matrix $\mathbf P$ and let's say $\bf Px = b$. My problem consists of
$$\begin{array}{ll} \text{minimize} & \| {\bf P} {\bf x} \|_2^2& \\ \text{subject to} & {\bf P} {\bf x} \geq {\bf y} \\ & \ell \leq {\bf 1}^\top {\bf x} \leq u \\ & x_i \in \{0,1\}\end{array}$$
where $\mathbf P$, $\mathbf y$, $\ell$, and $u$ are given. The purpose of $\mathbf x$ is to get specific parts of $\mathbf P$ into $\mathbf b$.
You need a mixed-integer quadratic programming solver for this, such as Mosek or Gurobi, available also for MATLAB, free for academia
With a modelling Toolbox such as YALMIP (developed by me) with some installed MIQP solver, you would conveniently solve it then as
However, with the trivial size you speak about, nothing will beat brute-force enumeration.