Consider the point $\vec{p} = (3,48,4,5,8) \in\mathbb{R}^{5}$, how many distinct paths are there from zero to $\vec{p}$ if the only movements allowed are unit movements in the directions $\vec{e}_{1}, \vec{e}_{2}, \vec{e}_{3}, \vec{e}_{4}, \vec{e}_{5}$?
Would this mean that we have $\frac{(3+48+4+5+8)!}{3!48!4!5!8!} = \frac{68!}{3!48!4!5!8!}$ distinct paths?
Your answer $\frac{(3+48+4+5+8)!}{3!48!4!5!8!} = \frac{68!}{3!48!4!5!8!}$ is exactly correct.
We have to 'line up' 68 moves, so that would suggest $68!$ possibilities, but since you have $3$ $e_1$-moves, they are indistinguishable in this line-up, so the $68!$ overcounts by a factor of $3!$, mneaning that you need to divide $68!$ by $3!$. But the same is true for the other dimensions.