Let $G$ be a group and $M$ a left $G-$module. It is well know that for some conditions all the cohomology groups $H^{i}(G,M)$, $i=0,1,2,.....$ vanish. The same can be do for the Hochschild cohomology groups $HH^{i}(A,M)$ of an associative algebra $A$ and an $A-$bomodule $M$....and so on in other contexts like cohomology of Lie algebras.
Mathematicians like Hochschild-Serre, Morris Hirsch and Rolf Farnsteiner stablished such that theorems.
My question is: why is it interesting that all the cohomology groups of a given algebraic structure vanish?
Is there a geometric interpretation for $H^{i}(G,M)=0$ for all $i=0,1,2....$?
What tells us about an algebra $A$ and a given $A-$bimodule $M$ the condition $HH^{i}(A,M)=0$ for all $i=0,1,2....$?
I'm sorry for my bad english.
This is a broad question. Let me comment it for Lie algebras, which you have mentioned.
For Lie algebras $L$, even for the adjoint module $M=L$, the vanishing of $H^n(L,L)$ for all $n\ge 0$ has very strong consequences, both algebraically and geometrically. Concerning geometric interpretations, $H^2(L,L)=0$ alone yields that $L$ is geometrically rigid. Also, the vanishing of $H^2(L,L)$ or $H^3(L,L)$ is important for deformation theory of Lie algebras.
Furthermore, Roger Carles has proved many algebraic properties following from the vanishing, namely that the solvable radical ${\rm rad}(L)$ then is necessarily nilpotent. Of course the center $Z(L)$ is trivial because of $H^0(L,L)=0$. If we also assume that $L$ is perfect, then Pirashvili has conjectured that $L$ is semisimple.
In general, if $H^1(L,M)=0$ for all finite-dimensional $L$-modules, then $L$ is semisimple. This is a "converse" of Whitehead's theorem in characteristic zero. Also $H^2(L,M)=0$ has strong consequences, almost forcing $L$ to be semisimple.