In a textbook I found the rather strange identity:
$$ \frac{2^4}{(5-2)(3-2)}+\frac{3^4}{(5-3)(3-2)}+\frac{5^4}{(5-3)(5-2)}= \frac{414}{6}=69 $$
just kind if out of nowhere and I wonder if it generalizes and why. Perhaps it is that:
$$ \frac{a^4}{(b-a)(c-a)}+\frac{b^4}{(c-b)(a-b)}+\frac{c^4}{(a-c)(b-c)} \tag{$\ast$} $$
is always an integer? On the same page I found the formula:
$$ \left|\begin{array}{cccc} 1 & a & a^2 & a^4 \\ 1 & b & b^2 & b^4 \\ 1 & c & c^2 & c^4 \\ 1 & d & d^2 & d^4 \\ \end{array} \right| = P \times (a+b+c+d)$$
My guess is that $P$ is short-hand for the product of all the different pairs of numbers:
$$ P = (a-b)(a-c)(a-d)(b-c)(b-d)(c-d) $$
This is not the right formula I'm afraid. However, I do see:
$$ \left|\begin{array}{cccc} 1 & 2 & 16 \\ 1 & 3 & 81 \\ 1 & 5 & 625 \end{array} \right| = P \times \stackrel{2}{C}(2,3,5)$$
which could mean anything. The book is in German - which I do not understand, and the man has invented this wonderful symbol $\stackrel{2}{C}$.
Mainly I am wondering if other integer identities can be found this way. Or is it only the case for $(a,b,c) = (2,3,5)$.
According to Wolfram Alpha the expression
$$\frac{a^4}{(b-a)(c-a)}+\frac{b^4}{(c-b)(b-a)}+\frac{c^4}{(c-a)(c-b)} \tag{$\ast$}$$ is not always an integer (see https://www.wolframalpha.com/input/?i=%5Cfrac%7Ba%5E4%7D%7B(b-a)(c-a)%7D%2B%5Cfrac%7Bb%5E4%7D%7B(c-b)(b-a)%7D%2B%5Cfrac%7Bc%5E4%7D%7B(c-a)(c-b)%7D,+a%3D3,b%3D5,c%3D7). But the expression you wrote
$$\frac{a^4}{(b-a)(c-a)}+\frac{b^4}{(c-b)(a-b)}+\frac{c^4}{(a-c)(b-c)} \tag{$\ast$}$$ is always an integer. (Note the difference with your example. The denominator of the second fraction changes sign).
With respect to the determinant note that:
\begin{align}\left|\begin{array}{cccc} 1 & a & a^2 & a^4 \\ 1 & b & b^2 & b^4 \\ 1 & c & c^2 & c^4 \\ 1 & d & d^2 & d^4 \\ \end{array} \right| & \\ &\underbrace{=}_{(1)}\left|\begin{array}{cccc} 1 & a & a^2 & a^4 \\ 0 & b-a & b^2-a^2 & b^4-a^4 \\ 0 & c-b & c^2-b^2 & c^4-b^4 \\ 0 & d-c & d^2-c^2 & d^4-c^4 \\ \end{array} \right| \\ &\underbrace{=}_{(2)}\left|\begin{array}{ccc} b-a & b^2-a^2 & b^4-a^4 \\ c-b & c^2-b^2 & c^4-b^4 \\ d-c & d^2-c^2 & d^4-c^4 \\ \end{array} \right|\\ &\underbrace{=}_{(3)}(b-a)(c-b)(d-c)\left|\begin{array}{ccc} 1 & b+a & b^3+b^2a+ba^2+a^3 \\ 1 & c+b & c^3+c^2b+cb^2+b^3 \\ 1 & d+c & d^3+d^2c+dc^2+c^3 \\ \end{array}\right| \end{align}
where in $(1)$ we have made $F_i-F_1\to F_i, i=2,3,4,$ in $(2)$ we have used the Laplacian's expansion using the first column and in $(3)$ we get out of the determinand $b-a$ from the first row, $c-b$ from the second one and $d-c$ from the third one.
Now, proceeding in a similar way we have \begin{align}\left|\begin{array}{ccc} 1 & b+a & b^3+b^2a+ba^2+a^3 \\ 1 & c+b & c^3+c^2b+cb^2+b^3 \\ 1 & d+c & d^3+d^2c+dc^2+c^3 \\ \end{array}\right| &\\&=\left|\begin{array}{ccc} 1 & b+a & b^3+b^2a+ba^2+a^3 \\ 0 & c-a & c^3+c^2b+cb^2-b^2a-ba^2-a^3 \\ 0 & d-b & d^3+d^2c+dc^2-c^2b-cb^2-b^3\\ \end{array}\right|\\&=\left|\begin{array}{ccc} c-a & c^3+c^2b+cb^2-b^2a-ba^2-a^3 \\ d-b & d^3+d^2c+dc^2-c^2b-cb^2-b^3\\ \end{array}\right|\\&=(d-b)(d-a)(c-a)(a+b+c+d).\end{align}
So, your guess about $P$ is correct.