Is it correct to replace $O(\epsilon) - O(\delta)$ by $ O(\epsilon)$ if $\epsilon \gg \delta$?

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Suppose I have an asymptotic estimate $K = O(\epsilon) - O(\delta)$, where $\epsilon \gg \delta$.

Is it correct then to write $K = O(\epsilon)$ ?

Additionally, what if I just have $\epsilon > \delta$? Would $K = O(\epsilon)$ still me correct?