Is it possible to define schemes without using sheaves?

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My understanding is that smooth manifolds can be defined either in the usual way (using smooth charts and atlases), or using sheaves (as a locally ringed space which is locally isomorphic to the sheaf of smooth functions on $\mathbb{R}^{n}$). However, schemes seem to only be defined using sheaves. Is it possible to define a scheme as a topological space which is locally homeomorphic to an affine scheme, such that the transition maps are all maps of affine schemes? Another way to phrase the question could be: given such a space, is it possible to recover a structure sheaf defining a scheme?