For a poset $(P, \leq)$ we say a subset $C\subseteq P$ is cofinal if for all $p\in P$ there is $c\in C$ such that $p\leq c$. We set $$\text{cf}(P,\leq) = \min\{|C|: C\subseteq P \text{ and } C \text{ is cofinal in } P\}.$$
Let $\omega^\omega$ be the set of all functions $f:\omega\to\omega$ ordered pointwise. Set ${\frak d} = \text{cf}(\omega^\omega)$.
Under $\sf CH$ it is known that ${\frak d} = 2^\omega$ which is regular. But are there other models of $\sf ZFC$ such that $\frak d$ is singular?
The dominating number $\mathfrak d$ is not necessarily regular. You can see in Theorem 2.5 of the reference below that it is consistent for $\mathfrak d$ to be any cardinal greater than or equal to $\mathfrak b$ (which, in turn, is regular) and less than or equal to $\mathfrak c=2^{\aleph_0}$ (which, against what you write in your question, is not necessarily regular).
The argument essentially goes back to Hechler, and Andreas provides references and details.