Given the double sum, which has a closed form of $H_{2n}$
$$\sum_{k=0}^{n}{n\choose k}\sum_{i=0}^{k}(-1)^i{k\choose i}H_{n+k-i}\tag1$$
Where $H_n$ is the Harmonic number
$(1)$ is quite an interesting sums which give a neat simple closed form, we encounters it while just messing a round with the sum calculator. How to go about proving it, we have not ideas.
How do we go about by showing that $(1)=H_{2n}$?
note: $$\sum_{k=0}^{n}{n\choose k}x^k=(1+x)^n\tag2$$
$$\sum_{k=1}^{n}(-1)^{k+1}{1\over k}{n\choose k}=H_n\tag3$$
This has nothing particular to do with harmonic numbers; it works for any sequence $a_n$.
The coefficient of $a_\ell$ in the sum $\sum_k{n\choose k}\sum_i (-1)^i {k\choose i} a_{n+k-i}$ is, with $n+k-i=\ell$, $$\sum_k {k\choose k-i}{n\choose k}(-1)^i =\sum_k {k\choose \ell-n}{n\choose k}(-1)^{k-(\ell-n)}={n\choose \ell-n}(1+(-1))^{2n-\ell}.\tag1$$ The second equation uses the identity, $$\sum_k{k\choose m}{n\choose k}x^{k-m}={n\choose m}(1+x)^{n-m}.\tag2$$
The right hand side of (1) shows that the coefficient of $a_\ell$ is equal to one if $\ell=2n$ and is equal to zero otherwise. Therefore $$\sum_k{n\choose k}\sum_i (-1)^i {k\choose i} a_{n+k-i}=a_{2n}. $$