Motivating Hypergeometric Series

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Are there a few 'nice' or 'natural' ways to motivate the existence of the Hypergeometric series

$$F(a,b;c:x) = 1 + \frac{ab}{c}x+\frac{1}{2!} \frac{a(a+1)b(b+1)}{c(c+1)}x^2+...?$$

Are there combinatorial or Physics interpretations for example?