Quartic Polynomial Manipulation

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I have a quartic polynomial in $x$ (too long to write here)

$f(x,c_1, c_2, c_2)$

where $c_1, c_2, c_3$ are constants which I have complete freedom over how to fix their values, as long as they are all greater than zero.

As this is a quartic, I have 4 roots to $f=0$ (two are usually imaginary and two real). I want to fix my constants so that I have two real, positive values of $x$.

At the moment I'm just plotting $f(x)$ with different values of $c_1, c_2, c_3$ and trying to pick these values so that my graph crosses the real positive axis twice. However so far I am unsuccessful.

Is there some analytical method of doing this?