We have $A,B,C$ three $n×n$ matrices with real entries. We know that $$ A^2 = -BC $$ and we want to show that $$ \det(AB-BA) × \det(AC-CA) \geq 0 \,. $$
We can easily show that for $n=2k$ we have $\det(B) × \det(C) \geq 0$, and for $n = 2k + 1$ we have $\det(B) × \det(C) \leq0$. Then for $n = 2k$ we can expand $\det(AB-BA)$ like $$ 2 × \det(A) × \det(B) - c_1 + c_2 - c_3 + c_4 - \dotsb +c_{n-2} - c_{n-1} $$ and expand $\det(AC-CA)$ like $$ 2 × \det(A) × \det(C) - d_1 + d_2 - d_3 + d_4 - \dotsb + d_{n-2} - d_{n-1} \,. $$ For $n = 2k + 1$, we can expand $\det(AB - BA)$ like $$ c_1 - c_2 + c_3 - c_4 + \dotsb + c_{n-2} - c_{n-1} $$ and $\det(AC - CA)$ like $$ d_1 - d_2 + d_3 - d_4 + \dotsb + d_{n-2} - d_{n-1} \,. $$ If we multiply these two expanded forms in every case $n = 2k$ and $n = 2k+1$, then we get an ugly answer and I don’t know we can check the sign like that. I am now stuck. Maybe we need to use eigenvalues? Please someone help me solve this problem.
Since $A^2+BC=0$, $$ \begin{aligned} &\quad\det(AB-BA)\det(AC-CA)\\ &=\det\pmatrix{AB-BA&0\\ A^2+CB&AC-CA}\\ &=\det\left[\pmatrix{A&-B\\ C&A}\pmatrix{B&-A\\ A&C}\right]\\ &=\det\left[\pmatrix{A&-B\\ C&A}\pmatrix{-I&0\\ 0&I}\pmatrix{A&-B\\ C&A}\pmatrix{0&I\\ I&0}\right]\\ &=\det\pmatrix{A&-B\\ C&A}\times(-1)^n\times\det\pmatrix{A&-B\\ C&A}\times(-1)^n\\ &=\det\pmatrix{A&-B\\ C&A}^2\ge0. \end{aligned} $$