Let $$S_{m,n}=\sum_{k=0}^{n}{m+k\choose m}^{-1}$$ Then $S_{0,n}=n+1, S_{1,n}=H_{n+1}.$
For $m>1$, let us consider the integral $$I_{m,k}=\int_{0}^{1} (1-x^{1/m})^k dx$$ which by using $x=\sin^{2m} t$ and Beta function, can be expressed as $$I_{m,k}=2m\int_{0}^{\frac{\pi}{2}}\sin^{2m-1} t ~ \cos^{2k+1} t~ dt= \frac{\Gamma(m+1) \Gamma(k+1)}{\Gamma(m+k+1)}={m+k\choose m}^{-1}.$$ Next, we can write $$S_{m,n}=\sum_{k=0}^{n} I_{m,k}=\int_{0}^{1}dx \sum_{k=0}^n (1-x^{1/m})^k=\int_{0}^{1} x^{-1/m}[1-(1-x^{1/m})^{n+1}]~ dx.$$ $$\implies S_{m,n}=\frac{m}{m-1}-\int_0^1 x^{-1/m}(1-x^{1/m})^{n+1} dx$$
Again by using $x=\sin^{2m} t$ and Beta-integral, we get $$S_{m.n}=\frac{m}{m-1}-2m\int_{0}^{\frac{\pi}{2}} \sin^{2m-3}~\cos^{2n+3} ~dt=\frac{m}{m-1}-\frac{\Gamma(m)\Gamma(n+2)}{\Gamma(m+m+1)}. $$ Upon simplification we have $$S_{m,n}=\frac{m}{m-1}\left[1-{m+n\choose m-1}^{-1}\right],m>1.$$
The question us how else this result can be obtained?
$$S_{m,n}(x)=\sum_{k=0}^{n}{m+k\choose m}^{-1} x^k=\Gamma(m+1)\sum_{k=0}^{n}\frac{ \Gamma (k+1)}{\Gamma (k+m+1)}x^k$$
$$S_{m,n}(x)=\, _2F_1(1,1;m+1;x)-\frac{\Gamma (m+1)\Gamma (n+2) }{\Gamma (m+n+2)} x^{n+1}\, _2F_1(1,n+2;m+n+2;x) $$
For $m \geq 2$ $$\, _2F_1(1,1;m+1;1)=\frac m{m-1}$$
Enjoy the simplification of
$$\frac{\Gamma (m+1)\Gamma (n+2) }{\Gamma (m+n+2)} \, _2F_1(1,n+2;m+n+2;1) $$