Is there anyone who can simplify this expression
$$\sinh\left(2\operatorname{arctanh}\left(e^{Hx}\right)\right)$$
Is it possible to this equal to be $-\operatorname{csch}(Hx)$ ?
In Wikipedia's "Hyperbolic functions" entry I saw that
$$\operatorname{arctanh}(x) = \frac{1}{2}\ln\frac{1+x}{1-x}$$
I tried to simplify it but I could not ...
Yes, it's possible to be equal. Using what you found and the hyperbolic function definitions, you have
$$\begin{equation}\begin{aligned} \sinh\left(2\operatorname{arctanh}\left(e^{Hx}\right)\right) & = \sinh\left(\ln\frac{1+e^{Hx}}{1-e^{Hx}}\right) \\ & = \frac{e^{\ln\frac{1+e^{Hx}}{1-e^{Hx}}} - e^{-\ln\frac{1+e^{Hx}}{1-e^{Hx}}}}{2} \\ & = \frac{\frac{1+e^{Hx}}{1-e^{Hx}} - \frac{1-e^{Hx}}{1+e^{Hx}}}{2} \\ & = \frac{\frac{1+2e^{Hx}+e^{2Hx}-(1-2e^{Hx} + e^{2Hx})}{(1-e^{Hx})(1+e^{Hx})}}{2} \\ & = \frac{\frac{4e^{Hx}}{1-e^{2Hx}}}{2} \\ & = \frac{2e^{Hx}}{{1-e^{2Hx}}} \end{aligned}\end{equation}\tag{1}\label{eq1A}$$
Also, you have
$$\begin{equation}\begin{aligned} -\operatorname{csch}(Hx) & = -\frac{2e^{Hx}}{e^{2Hx} - 1} \\ & = \frac{2e^{Hx}}{1 - e^{2Hx}} \end{aligned}\end{equation}\tag{2}\label{eq2A}$$
As you can see, \eqref{eq1A} and \eqref{eq2A} match.