The formula for the exponent of the highest power of prime $p$ dividing $n!$ is $\sum \frac{n}{p^k}$, but the question is $n=1000!$ (really, it has the factorial) and $p=5$.
When I use Wolfram Alpha , I panicked because the number has $2,567$ decimal digits.
I think if I write this number I'd need paper all the way to the Amazon.
Perhaps I misunderstand the formula?
It’s $n$ in the numerator, not $n!$. It turns out that only the first four terms of the sum are non-zero:
$$\begin{align*} \sum_{k\ge 1}\left\lfloor\frac{1000}{5^k}\right\rfloor&=\left\lfloor\frac{1000}5\right\rfloor+\left\lfloor\frac{1000}{25}\right\rfloor+\left\lfloor\frac{1000}{125}\right\rfloor+\left\lfloor\frac{1000}{625}\right\rfloor+\left\lfloor\frac{1000}{3125}\right\rfloor+\ldots\\ &=200+40+8+1+0+0+0+\ldots\\ &=249\;. \end{align*}$$