We have 2 Truchet tiles and a flattened cube as shown.

We randomly place copies of the tiles into faces of the flattened cube.
- Find the probability that the circular arcs on the Truchet tiles will form one loop, two loops, three loops and four loops?
- If we divide each face of the flattened cube into 2x2 grid of squares, what will be the new probability for part (1)?
I saw a journal about the three-dimensional Truchet tiles and they want the beginners to start with the basic question. I don't have any idea to start with. I'm thinking of defining a binary variable but it doesn't seem so promising.
A cube has six sides and (given your particular Truchet pattern) there are exactly two choices of orientation for each side. Thus, there are only 64 total possibilities. You could simply enumerate them and count the possibilities.
Furthermore, as observed in the comments by Steven Stadnicki, we can cut this number in half by fixing the orientation of one side. That brings the number of configurations to examine down to 32, which is quite doable. According to his count (based on the images below), we have
I enumerated all possibilities and generated the corresponding images with Mathematica; the results are below. This could certainly be pushed further to obtain a purely algorithmic approach. In the code shown after the images, each loop could be described as a triple $(p,v,\pm 1)$, where $p$ and $v$ correspond to the
perpandvertin the code below and $\pm 1$ chooses between the loops on the side. Since each loop has two easily determined endpoints and two loops are adjacent iff they share an endpoint, one could write a function to determine adjacency between loops. This would allow you to write down a graph theoretic description of the problem and phrase the question in terms of connected components of a graph. This would come in handy if the problem were generalized by reducing the symmetry in the sides so that you could have up to four possible side orientations - or even more if there were multiple possible sides. I don't think I'll worry about that today, though.Code
Since several folks specifically asked, here is the Mathematica code that I used to generate the images. Since this is mathematics site, as opposed to a coding site, I will not elaborate on this unless there are specific question. Clearly, though, the code is fundamental to the approach.