Useful restrictions for prime factors of a sum of two powers with coprime exponents

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Every prime factor of a number of the form

$$a^2+b^2$$

with gcd(a,b)=1 has -1 as a quadratic residue.

Does this work only for exponents with a common factor, or are there useful restrictions also for coprime exponents ?

For example , are there any restrictions for the prime factors of numbers of the form

$$a^4 + b^9$$

with gcd(a,b)=1 ?